NASOPHARYNGEAL CARCINOMA IN PANYABUNGAN DISTRICT HOSPITAL

Nasopharyngeal carcinoma in situ in nasopharyngeal carcinoma.

AIMS To assess the presence of carcinoma in situ (CIS) in patients with nasopharyngeal carcinoma (NPC) and to see if the number of biopsy sites facilitates detection of CIS. METHODS Formalin fixed, paraffin wax embedded biopsy specimens (n = 285) from 187 patients with NPC in 1987 were studied for the presence of CIS as well as for the histological assessment of the subtype of CIS. RESULTS ...

Demographic study of nasopharyngeal carcinoma in a hospital setting.

OBJECTIVES To highlight demographic pattern of nasopharyngeal carcinoma and determine mode and stage of presentation. DESIGN Prospective analytical study. SETTING Kenyatta National Hospital (KNH)/University of Nairobi, Kenya. SUBJECTS One hundred and twenty five patients seen at the ENT department of KNH. These were either referred from other peripheral hospitals or first seen at KNH and ...

MicroRNAs in nasopharyngeal carcinoma

It is becoming increasingly evident that aberrantly expressed microRNAs (miRNAs) are responsible for a number of disease processes, including cancer initiation and progression. miRNAs have been implicated as key players in numerous neoplasms, including nasopharyngeal carcinoma (NPC). Functionally, deregulation of miRNAs that act either as tumour suppressors or oncogenes results in numerous canc...

Exosomes in Nasopharyngeal Carcinoma

Exosomes are nanosized (30-100nm) membrane microvesicles secreted through a complex cellular process. Exosomes contain a variety of bioactive molecules, such as proteins, microRNAs(miRNAs or miRs) and long non-coding RNAs (lncRNAs), playing an important role in the cell-to-cell substance transportation and signal transduction. Nasopharyngeal carcinoma-related exosomes (NPC-Exo) have been identi...

Epigenetics in Nasopharyngeal Carcinoma